![]() ![]() Some cases presented with features resembling serotonin syndrome.Ĭitalopram should not be given to patients receiving MAOIs, including selegiline, in daily doses exceeding 10mg/day.Ĭitalopram should not be given for fourteen days after discontinuation of an irreversible MAOI or for the time specified after discontinuation of a reversible MAOI (RIMA) as stated in the prescribing text of the RIMA. Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. Consequently doses of tablets correspond to doses of drops as follows: The resulting solution must be drunk immediately by the patient.Ĭitalopram oral drops can be taken as a single daily dose, at any time of day, without regard to food intake.Ĭitalopram oral drops have approximately 25% increased bioavailability compared to tablets. ![]() The dose may be increased to a maximum of 16mg (8 drops) daily depending on individual patient response, (see section 5.2).Ĭitalopram 40mg/ml Oral drops should only be mixed with water, orange or apple juice. No information is available in cases of severe renal impairment (creatinine clearance <20ml/min).Īn initial dose of 8mg (4 drops) daily during the first two weeks of treatment is recommended for patients who are known to be poor metabolisers with respect to CYP2C19. Caution and extra careful dose titration is advised in patients with severely reduced hepatic function (see section 5.2).ĭosage adjustment is not necessary in cases of mild or moderate renal impairment. The recommended maximum dose for the elderly is 16mg (8 drops) daily.Ĭitalopram should not be used in the treatment of children and adolescents under the age of 18 years (see section 4.4).Īn initial dose of 8mg (4 drops) daily for the first two weeks of treatment is recommended in patients with mild or moderate hepatic impairment.ĭepending on individual patient response, the dose may be increased to a maximum of 16mg (8 drops) daily. Dosage adjustments should be made carefully on an individual patient basis, to maintain the patients at the lowest effective dose.įor elderly patients the dose should be decreased to half of the recommended dose, e.g. Although there may be an increased potential for undesirable effects at higher doses, if after some weeks on the recommended dose insufficient response is seen some patients may benefit from having their dose increased gradually. Dependent on individual patient response, the dose may be increased to a maximum of 32mg (16 drops) daily.Ī low initial starting dose is recommended to minimise the potential worsening of panic symptoms, which is generally recognised to occur early in the treatment of this disorder. Patients with depression should be treated for a sufficient period of at least 6 months to ensure that they are free from symptoms.Ī single oral dose of 8mg (4 drops) is recommended for the first week before increasing the dose to 16mg (8 drops) daily. Dosage adjustments should be made carefully on an individual patient basis, to maintain the patient at the lowest effective dose. Dependent on individual patient response, the dose may be increased to a maximum of 32mg (16 drops) daily.Īs with all antidepressant medicinal products, dosage should be reviewed and adjusted if necessary within 3 to 4 weeks of initiation of therapy and thereafter as judged clinically appropriate. Date of first authorisation/renewal of the authorisationĬitalopram should be administered as a single oral dose of 16mg (8 drops) daily. 6.6 Special precautions for disposal and other handling.4.7 Effects on ability to drive and use machines.4.5 Interaction with other medicinal products and other forms of interaction.4.4 Special warnings and precautions for use.4.2 Posology and method of administration.Show table of contents Hide table of contents
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